Umbelliprenin is Potentially Toxic Against the HT29, CT26, MCF-7, 4T1, A172, and GL26 Cell Lines, Potentially Harmful Against Bone Marrow-Derived Stem Cells, and Non-Toxic Against Peripheral Blood Mononuclear Cells
نویسندگان
چکیده
منابع مشابه
umbelliprenin is potentially toxic against the ht29, ct26, mcf-7, 4t1, a172, and gl26 cell lines, potentially harmful against bone marrow-derived stem cells, and non-toxic against peripheral blood mononuclear cells
conclusions our findings indicate that umbelliprenin exhibits concentration-dependent inhibitory effects on various cell types; it is potentially toxic against the ht29, ct26, mcf-7, 4t1, a172, and gl26 cell lines, potentially harmful against bmdscs, and non-toxic against pbmcs. therefore, if our results are approved in the future, umbelliprenin can be an appropriate candidate for developing tr...
متن کاملUmbelliprenin is Potentially Toxic Against the HT29, CT26, MCF-7, 4T1, A172, and GL26 Cell Lines, Potentially Harmful Against Bone Marrow-Derived Stem Cells, and Non-Toxic Against Peripheral Blood Mononuclear Cells
BACKGROUND Resistance to chemotherapy is a growing concern, thus natural anticancer agents are drawing the attention of many scientists and clinicians. One natural anticancer agent, umbelliprenin, is a coumarin produced by many species of Ferula. OBJECTIVES We aimed to examine the inhibitory effect of umbelliprenin on human and mouse bone marrow-derived stem cells (BMDSCs), peripheral blood m...
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ژورنال
عنوان ژورنال: Iranian Red Crescent Medical Journal
سال: 2016
ISSN: 2074-1804,2074-1812
DOI: 10.5812/ircmj.35167